NOAEL Studies Cosmetic Ingredient

Isodecyl Acrylate NOAEL Studies

INCI: ISODECYL ACRYLATE

CAS: 1330-61-6

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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NTP_ICE_acute_oral 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_acute_oral LD50 =12000 mg/kg bw Rat oral acute Rat Acute Oral Toxicity record_id=acute_oral_2278; row=12038; data_type=In Vivo; mixture=Chemical; chemical_name=Isodecyl acrylate; preferred_name=Isodecyl acrylate; dtxsid=DTXSID7027386; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID7027386; source_file=acute_oral.xlsx
ToxValDB_ECHA_IUCLID 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECHA_IUCLID LOAEC =226 mg/m3 Rat inhalation subchronic; 90 days subchronic QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66059786e4b063812d6fa765; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11766/7/6/3?documentUUID=f9d922a3-4001-4787-8685-231051d34466; YEAR=2013; ORIGINAL_YEAR=2013; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Inhalation_15829003_15829004_15829005_15829006:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_f8e81d6b9f00687e77e18e6e31da39e7
ToxValDB_ECHA_IUCLID LOAEC =753 mg/m3 Rat inhalation subchronic; 90 days subchronic QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66059786e4b063812d6fa765; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11766/7/6/3?documentUUID=f9d922a3-4001-4787-8685-231051d34466; YEAR=2013; ORIGINAL_YEAR=2013; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Inhalation_15829003_15829004_15829005_15829006:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_8cb8e2a284ca7ba79c2f6cdaa24a0a1f
ToxValDB_ECHA_IUCLID NOAEC =75 mg/m3 Rat inhalation subchronic; 90 days subchronic QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66059786e4b063812d6fa765; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11766/7/6/3?documentUUID=f9d922a3-4001-4787-8685-231051d34466; YEAR=2013; ORIGINAL_YEAR=2013; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Inhalation_15829003_15829004_15829005_15829006:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_a2353644ccc86e7f6d1b854a6f5d3623
ToxValDB_ECHA_IUCLID NOAEL =1000 mg/kg bw/day Rat oral - reproduction developmental QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaa8be4b0a7c65d1b65ee; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11766/7/9/2?documentUUID=f9d922a3-4001-4787-8685-231051d34466; YEAR=2013; ORIGINAL_YEAR=2013; STUDY_GROUP=ECHA IUCLID:15857032:M/F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_66cadba8136a01f6ac85fa09dcf8112f
ToxValDB_GESTIS_DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_GESTIS_DNEL DNEL local =37.5 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15632849:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_29bef3a1cf8ab9b5970fe47548018921
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier WET3U98PW2 UNII - - - chemical {"approval_status":null,"molecular_formula":"C13H24O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"WET3U98PW2"}
openFDA substances FDA UNII substance identifier WET3U98PW2 UNII - - - chemical {"approval_status":null,"molecular_formula":"C13H24O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"WET3U98PW2"}
openFDA substances FDA UNII substance identifier WET3U98PW2 UNII - - - chemical {"approval_status":null,"molecular_formula":"C13H24O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"WET3U98PW2"}
openFDA substances FDA UNII substance identifier WET3U98PW2 UNII - - - chemical {"approval_status":null,"molecular_formula":"C13H24O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"WET3U98PW2"}