Is Isodecyl Acrylate safe in cosmetics?
Isodecyl Acrylate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.
Isodecyl Acrylate
Also known as: 2-Propenoic acid, isodecyl ester, Acrylic acid, isodecyl ester, Ageflex FA-10, EINECS 215-542-5, Isodecyl alcohol, acrylate (+1 more)
INCI: ISODECYL ACRYLATE
Isodecyl Acrylate (CAS 1330-61-6) is a cosmetic cosmetic ingredient functioning as Monomer used to manufacture acrylate copolymers; not used as free monomer in. Reported NOAEL =1000 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 1330-61-6 →
Auto-generated CPSR Part A draft with source citations
Function
Monomer used to manufacture acrylate copolymers; not used as free monomer in cosmetics
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
8-methylnonyl prop-2-enoate
InChIKey
LVGFPWDANALGOY-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted only as polymerized copolymer component. Free monomer not intended for direct cosmetic use.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Isodecyl Acrylate.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Isodecyl Acrylate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =1000 mg/kg bw/day | oral | Rat | reproduction developmental | ToxValDB_ECHA_IUCLID |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Skin Eye Respiratory Irritation
The lower molecular weight esters of acrylic acids are irritants to skin, eyes and mucous membranes. /Acrylic acid esters/
Source: Hazardous Substances Data Bank (HSDB)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
No specific technical function
Expert Verdict
Expert safety assessment and concern-level summary for Isodecyl Acrylate.
Regulatory Flags
potential-allergen
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Isodecyl Acrylate by CAS number or substance name.
Studies
4
Lowest NOAEL
1000 mg/kg bw/day
Highest NOAEL
1000 mg/kg bw/day
ToxValDB_ECHA_IUCLID
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip
Known Synonyms
2-Propenoic acid, isodecyl ester
Acrylic acid, isodecyl ester
Ageflex FA-10
EINECS 215-542-5
Isodecyl alcohol, acrylate
Isodecyl propenoate
Chemical Function
No specific technical function
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3186945
Frequently Asked Questions
Is Isodecyl Acrylate allowed in the EU?
Isodecyl Acrylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Isodecyl Acrylate do in cosmetics?
Isodecyl Acrylate functions as: Monomer used to manufacture acrylate copolymers; not used as free monomer in cosmetics. It is classified as a cosmetic ingredient in our database. CAS number: 1330-61-6.
What is the NOAEL for Isodecyl Acrylate?
The NOAEL (No Observed Adverse Effect Level) for Isodecyl Acrylate is =1000 mg/kg bw/day based on a reproduction developmental study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.
Is Isodecyl Acrylate used outside cosmetics?
Isodecyl Acrylate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Isodecyl Acrylate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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