Isosteareth-22

INCI: ISOSTEARETH-22

CAS Number
52292-17-8 (generic isosteareth series)
Function
Surfactant - Cleansing; Surfactant - Emulsifying
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no specific prohibition or restriction; CIR Expert Panel reviewed alkyl PEG ethers (including isosteareth compounds) and concluded safe as used when formulated to be non-irritating

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Potential residual 1,4-dioxane and ethylene oxide from ethoxylation process; must be purified to acceptable trace levels. High HLB nonionic emulsifier; 22 moles of ethylene oxide yield strong hydrophilicity, excellent O/W emulsification and solubilization capacity

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Concern Level: Moderate

Frequently Asked Questions

Is Isosteareth-22 safe in cosmetics?

Potential residual 1,4-dioxane and ethylene oxide from ethoxylation process; must be purified to acceptable trace levels. High HLB nonionic emulsifier; 22 moles of ethylene oxide yield strong hydrophilicity, excellent O/W emulsification and solubilization capacity The EU classifies Isosteareth-22 as "prohibited". Safety rating: MODERATE.

Is Isosteareth-22 allowed in the EU?

Isosteareth-22 EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Isosteareth-22 do in cosmetics?

Isosteareth-22 functions as: Surfactant - Cleansing; Surfactant - Emulsifying. It is classified as a cosmetic ingredient in our database. CAS number: 52292-17-8 (generic isosteareth series).

What is the Margin of Safety for Isosteareth-22?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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