Regulatory Status
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Safety Data
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Expert Verdict
Strong anti-vitamin K activity (anticoagulant), documented reproductive toxicity and teratogenicity in animal studies, potential phototoxicity; systemic absorption through skin is a concern. A naturally occurring 1,4-naphthoquinone isolated from Tabebuia (pau d'arco) bark; shows broad-spectrum antimicrobial and antiparasitic activity in research; its toxicity profile makes cosmetic use problematic
Frequently Asked Questions
Is Lapachol safe in cosmetics?
Strong anti-vitamin K activity (anticoagulant), documented reproductive toxicity and teratogenicity in animal studies, potential phototoxicity; systemic absorption through skin is a concern. A naturally occurring 1,4-naphthoquinone isolated from Tabebuia (pau d'arco) bark; shows broad-spectrum antimicrobial and antiparasitic activity in research; its toxicity profile makes cosmetic use problematic The EU classifies Lapachol as "prohibited". Safety rating: MODERATE.
Is Lapachol allowed in the EU?
Lapachol EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Lapachol do in cosmetics?
Lapachol functions as: Antimicrobial, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 84-79-7.
What is the Margin of Safety for Lapachol?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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