Poor Cosmetic Ingredient

Larrea Mexicana Extract

INCI: LARREA MEXICANA EXTRACT

CAS Number
84603-72-5
Function
Fragrance, viscosity controlling
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status restricted
US Notes Not specifically banned in cosmetics under 21 CFR; FDA NDGA warnings apply to the genus

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Same genus as L. tridentata and L. divaricata with all Larrea species producing NDGA; limited species-specific safety data requiring NDGA content quantification; hepatotoxicity risk applies across the genus with usage-based limits in China (0.11% leave-on, 0.2% rinse-off) rather than toxicologically derived restrictions.

⚠️
Concern Level: High

Regulatory Flags

plant-extract fragrance-component

Frequently Asked Questions

Is Larrea Mexicana Extract safe in cosmetics?

Same genus as L. tridentata and L. divaricata with all Larrea species producing NDGA; limited species-specific safety data requiring NDGA content quantification; hepatotoxicity risk applies across the genus with usage-based limits in China (0.11% leave-on, 0.2% rinse-off) rather than toxicologically derived restrictions. The EU classifies Larrea Mexicana Extract as "permitted". Safety rating: POOR.

Is Larrea Mexicana Extract allowed in the EU?

Larrea Mexicana Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Larrea Mexicana Extract do in cosmetics?

Larrea Mexicana Extract functions as: Fragrance, viscosity controlling. It is classified as a cosmetic ingredient in our database. CAS number: 84603-72-5.

What is the Margin of Safety for Larrea Mexicana Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Larrea Mexicana Extract compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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