Moderate Cosmetic Ingredient NOAEL Data

Lauraldehyde

INCI: LAURALDEHYDE (ALSO KNOWN AS DODECANAL, ALDEHYDE C-12 LAURIC)

CAS Number
112-54-9
Function
Fragrance ingredient
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed. Recognized as a fragrance ingredient; not specifically prohibited or restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Lauraldehyde. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 20000 ppm oral rat oral REACH

Expert Verdict

As an aliphatic aldehyde, it can be a skin and mucous membrane irritant. Aldehydes are chemically reactive (can form Schiff bases with proteins), presenting potential sensitization risk at higher concentrations. Standard aldehyde handling precautions apply in formulation. A straight-chain C12 aldehyde with a characteristic fatty-waxy, citrus-floral scent. Famously used in Chanel No. 5 (1921). In alcoholic perfume bases, it can form diethyl acetals with no significant impact on odor profile

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Concern Level: Moderate

Regulatory Flags

potential-allergen fragrance-component epa_safer_alternative ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Lauraldehyde safe in cosmetics?

As an aliphatic aldehyde, it can be a skin and mucous membrane irritant. Aldehydes are chemically reactive (can form Schiff bases with proteins), presenting potential sensitization risk at higher concentrations. Standard aldehyde handling precautions apply in formulation. A straight-chain C12 aldehyde with a characteristic fatty-waxy, citrus-floral scent. Famously used in Chanel No. 5 (1921). In alcoholic perfume bases, it can form diethyl acetals with no significant impact on odor profile The EU classifies Lauraldehyde as "restricted". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.

Is Lauraldehyde allowed in the EU?

Lauraldehyde EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Lauraldehyde do in cosmetics?

Lauraldehyde functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 112-54-9.

What is the Margin of Safety for Lauraldehyde?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Lauraldehyde?

The NOAEL (No Observed Adverse Effect Level) for Lauraldehyde is 20000 ppm based on a oral study via oral route in rat. Source: REACH.

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