Excellent Cosmetic Ingredient NOAEL Data

Lauric/Myristic/Palmitic/Stearic Glycerides

INCI: LAURIC/MYRISTIC/PALMITIC/STEARIC GLYCERIDES

CAS Number
67254-73-3
Function
Skin conditioning agent
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” fatty acid glycerides not restricted under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

4 study endpoints found for Lauric/Myristic/Palmitic/Stearic Glycerides. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 14571 mg/kg bw/day oral syrian hamster Chronic COSMOS_DB
NOAEL 18000 mg/kg bw/day oral syrian hamster Subchronic COSMOS_DB
NOAEL 6000 mg/kg bw/day oral rat Carcinogenicity COSMOS_DB
dose_tested 14571 mg/kg bw/day oral syrian hamster Chronic COSMOS_DB

Expert Verdict

Constituent fatty acids (lauric, myristic, palmitic, stearic) individually assessed as safe by CIR.

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Concern Level: None

Regulatory Flags

fda_food_additive

Frequently Asked Questions

Is Lauric/Myristic/Palmitic/Stearic Glycerides safe in cosmetics?

Constituent fatty acids (lauric, myristic, palmitic, stearic) individually assessed as safe by CIR. The EU classifies Lauric/Myristic/Palmitic/Stearic Glycerides as "permitted". Safety rating: EXCELLENT. 4 toxicological study endpoint(s) are available in our database.

Is Lauric/Myristic/Palmitic/Stearic Glycerides allowed in the EU?

Lauric/Myristic/Palmitic/Stearic Glycerides EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Lauric/Myristic/Palmitic/Stearic Glycerides do in cosmetics?

Lauric/Myristic/Palmitic/Stearic Glycerides functions as: Skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 67254-73-3.

What is the Margin of Safety for Lauric/Myristic/Palmitic/Stearic Glycerides?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Lauric/Myristic/Palmitic/Stearic Glycerides?

The NOAEL (No Observed Adverse Effect Level) for Lauric/Myristic/Palmitic/Stearic Glycerides is 14571 mg/kg bw/day based on a Chronic study via oral route in syrian hamster. A total of 4 study endpoints are available. Source: COSMOS_DB.

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