Good Cosmetic Ingredient NOAEL Data

Lauroyl/Myristoyl Methyl Glucamide

INCI: LAUROYL/MYRISTOYL METHYL GLUCAMIDE

CAS Number
287735-50-6
Function
Hair conditioning, skin conditioning (emollient), surfactant-cleansing, viscosity controlling
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not listed in 21 CFR prohibited/restricted lists

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

4 study endpoints found for Lauroyl/Myristoyl Methyl Glucamide. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 200 mg/kg bw/day oral rat oral REACH
NOAEL 750 mg/kg bw/day oral rat oral REACH
NOAEL 200 mg/kg bw/day oral rat oral REACH
NOAEL 250 mg/kg bw/day oral rat oral REACH

Expert Verdict

Limited ingredient-specific toxicology data publicly available; however, methyl glucamide surfactants as a class are considered among the mildest surfactants. Read-across from lauroyl methyl glucamide and cocoyl methyl glucamide is well-supported.

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Concern Level: Low

Frequently Asked Questions

Is Lauroyl/Myristoyl Methyl Glucamide safe in cosmetics?

Limited ingredient-specific toxicology data publicly available; however, methyl glucamide surfactants as a class are considered among the mildest surfactants. Read-across from lauroyl methyl glucamide and cocoyl methyl glucamide is well-supported. The EU classifies Lauroyl/Myristoyl Methyl Glucamide as "permitted". Safety rating: GOOD. 4 toxicological study endpoint(s) are available in our database.

Is Lauroyl/Myristoyl Methyl Glucamide allowed in the EU?

Lauroyl/Myristoyl Methyl Glucamide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Lauroyl/Myristoyl Methyl Glucamide do in cosmetics?

Lauroyl/Myristoyl Methyl Glucamide functions as: Hair conditioning, skin conditioning (emollient), surfactant-cleansing, viscosity controlling. It is classified as a cosmetic ingredient in our database. CAS number: 287735-50-6.

What is the Margin of Safety for Lauroyl/Myristoyl Methyl Glucamide?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Lauroyl/Myristoyl Methyl Glucamide?

The NOAEL (No Observed Adverse Effect Level) for Lauroyl/Myristoyl Methyl Glucamide is 200 mg/kg bw/day based on a oral study via oral route in rat. A total of 4 study endpoints are available. Source: REACH.

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