Regulatory Status
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Safety Data
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Expert Verdict
SDS indicates skin irritation (H315), serious eye irritation (H319), and potential respiratory irritation (H335). Limited published cosmetic-specific toxicology data; no NOAEL established for dermal route. Structurally a flavanone with generally favorable toxicology profile, but CPSR requires ingredient-specific data for novel use levels above approximately 0.1%.
Regulatory Flags
Frequently Asked Questions
Is Liquiritigenin safe in cosmetics?
SDS indicates skin irritation (H315), serious eye irritation (H319), and potential respiratory irritation (H335). Limited published cosmetic-specific toxicology data; no NOAEL established for dermal route. Structurally a flavanone with generally favorable toxicology profile, but CPSR requires ingredient-specific data for novel use levels above approximately 0.1%. The EU classifies Liquiritigenin as "permitted". Safety rating: MODERATE.
Is Liquiritigenin allowed in the EU?
Liquiritigenin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Liquiritigenin do in cosmetics?
Liquiritigenin functions as: Antioxidant, skin conditioning, skin lightening (tyrosinase inhibition). It is classified as a cosmetic ingredient in our database. CAS number: 578-86-9 [^1_11].
What is the Margin of Safety for Liquiritigenin?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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