NOAEL Studies Cosmetic Ingredient

Magnesium Hydroxide NOAEL Studies

INCI: MAGNESIUM HYDROXIDE

CAS: 1309-42-8

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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COSMOS_DB 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
COSMOS_DB NOAEL 100 mg/kg bw/day rat oral 56 day Special Toxicology Study US FDA CFSAN PAFA; US FDA CFSAN PAFA Study
COSMOS_DB NOAEL 50 mg/kg bw/day rat oral 255 day Chronic US FDA CFSAN PAFA; US FDA CFSAN PAFA Study
ToxValDB_ECHA_IUCLID 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECHA_IUCLID NOAEL >=1000 mg/kg bw/day Rat oral - developmental GUIDELINE=other:; QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eac00e4b0a7c65d1bcee0; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/5837/7/9/3?documentUUID=a573366d-c344-49dd-bac0-2e83d9a6b056; YEAR=1989; ORIGINAL_YEAR=1989; STUDY_GROUP=ECHA IUCLID:15820995:-:-fetal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_3aa0078b5f5ae715746da6712efd2dcd
ToxValDB_GESTIS_DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_GESTIS_DNEL DNEL systemic =21.6 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15633133:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_b8c18467e230fdb6b665e05f8147ec2a
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier NBZ3QY004S UNII - - - chemical {"approval_status":null,"molecular_formula":"Mg.2HO","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"NBZ3QY004S"}
openFDA substances FDA UNII substance identifier NBZ3QY004S UNII - - - chemical {"approval_status":null,"molecular_formula":"Mg.2HO","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"NBZ3QY004S"}
openFDA substances FDA UNII substance identifier NBZ3QY004S UNII - - - chemical {"approval_status":null,"molecular_formula":"Mg.2HO","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"NBZ3QY004S"}
openFDA substances FDA UNII substance identifier NBZ3QY004S UNII - - - chemical {"approval_status":null,"molecular_formula":"Mg.2HO","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"NBZ3QY004S"}