Magnesium Hydroxide

Also known as: Magnesium hydroxide (Mg(OH)2), EINECS 215-170-3, Hydro-mag MA, Lycal 96 HSE, Magmesia hydrate (+6 more)

INCI: MAGNESIUM HYDROXIDE

Magnesium Hydroxide (CAS 1309-42-8) is a cosmetic cosmetic ingredient functioning as Absorbent, pH buffering/neutralizing agent, filler, texturizer. NOAEL 1000 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.

View industrial chemical safety profile for CAS 1309-42-8 →

Auto-generated CPSR Part A draft with source citations
Function
Absorbent, pH buffering/neutralizing agent, filler, texturizer
Safety Rating
MODERATE

Chemistry & Identifiers

Formula
H2MgO2
MW
58.32 g/mol
EC Number
215-170-3
PubChem CID
73981
IUPAC Name
magnesium dihydroxide
InChIKey
VTHJTEIRLNZDEV-UHFFFAOYSA-L

Regulatory Status

EU EU Status restricted
US US Status permitted
US Notes Allowed - not on FDA's prohibited/restricted list for cosmetics; also has GRAS status as a food additive

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Magnesium Hydroxide.

Calculate MoS for your specific formulation with the MoS Calculator.

Pre-Calculated Safety Assessment

Pre-calculated NOAEL → SED → MoS audit trail for Magnesium Hydroxide across SCCS product categories, with measured dermal absorption where available.

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
100,000 - 1,000,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Additional Ingredient Properties

3 property records from structured ingredient metadata.

deodorant
{"cas_number": "1309-42-8", "ingredient_class": "odor_neutralizer", "mechanism_of_action": "pH_modification", "antiperspirant_efficacy_sweat_reduction_pct": "0", "deodorant_efficacy_hours": "8-16", "odor_reduction_pct": "55-75", "bacteriostatic": "limited", "bactericidal": "no", "microbiome_impact": "neutral", "axillary_microbiome_effect": "pH modification", "pH_modification_range": "alkalinizes t…
ecotoxicity
{"biodegradable": "no", "biodegradation_days": "non-biodegradable", "bioaccumulative": "no", "aquatic_toxicity_level": "low", "coral_reef_safe": "yes", "marine_toxicity": "low toxicity", "freshwater_toxicity": "minimal impact", "soil_toxicity": "inert mineral", "endocrine_disruptor": "no", "persistent_organic_pollutant": "no", "microplastic": "no", "nano_particle": "no", "hawaii_banned": "no", "eu…
mineral_clay
{"cas_number": "1309-42-8", "ingredient_class": "magnesium_compound", "chemical_formula": "Mg(OH)2", "mineral_origin": "synthetic", "particle_size_range_um": "0.1-10", "surface_area_m2_per_g": "10-40", "crystal_structure": "hexagonal", "color_appearance": "white", "opacity": "opaque", "refractive_index": "1.58", "oil_absorption_g_per_100g": "40-80", "water_absorption_capacity": "80-150%", "surface…

PubChem Annotations

Safety and regulatory annotations from PubChem (NCBI) aggregated sources.

Regulatory (2)
JECFA Evaluation
MAGNESIUM HYDROXIDE | 1965 | NOT LIMITED | NMRS 40/TRS 339-JECFA 9/16 | FAS 67.29/NMRS 40A,B,C-JECFA 9/159
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
EU Food Improvement
Food additives
Source: EU Food Improvement Agents

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Absorbent Adhesion/cohesion promoter Binder Conductive agent Drier Dye Filler Flame retardant Flavouring and nutrient Processing aids not otherwise specified
Regulatory List Membership (2)
EPA Safer Chemical Ingredients List (SCIL) FDA Substances Added to Food (EAFUS)

Expert Verdict

Expert safety assessment and concern-level summary for Magnesium Hydroxide.

Regulatory Flags

epa_safer_alternative fda_food_additive jecfa_safe

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Magnesium Hydroxide by CAS number or substance name.

Studies
18
Lowest NOAEL
299 mg/kg bw/day
Highest NOAEL
6810 mg/kg bw/day
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip

Known Synonyms

Magnesium hydroxide (Mg(OH)2) EINECS 215-170-3 Hydro-mag MA Lycal 96 HSE Magmesia hydrate Magnesium hydroxide gel Nemalite UNII-NBZ3QY004S Magnesia, [Milk of] Mg(OH)2 magnesium hydrate

Chemical Function

pH regulating agent Absorbent Flame retardant Binder

Regulatory Lists

inert_ingredient; Pesticides active_ingredient; animal_products; Europe; pharmaceutical; residue Europe; supplements Europe; food_additive; supplements Europe; plastic_additive food_additive; Substances Added to Food (formerly EAFUS) (2/2019) SCIL (9/2019) Canada; pharmaceutical Canada; pharmaceutical inert_ingredient; non_food_use; Pesticides

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA CAS match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Compound
MAGNESIUM HYDROXIDE
ChEMBL ID
CHEMBL1200718
Max Phase
4
Adverse Event Associations
4173
View full pharmaceutical profile →

Frequently Asked Questions

Is Magnesium Hydroxide safe in cosmetics?

Magnesium Hydroxide has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.

Is Magnesium Hydroxide allowed in the EU?

Magnesium Hydroxide EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Magnesium Hydroxide do in cosmetics?

Magnesium Hydroxide functions as: Absorbent, pH buffering/neutralizing agent, filler, texturizer. It is classified as a cosmetic ingredient in our database. CAS number: 1309-42-8.

Is Magnesium Hydroxide used outside cosmetics?

Magnesium Hydroxide also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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