Moderate Cosmetic Ingredient NOAEL Data

Magnesium Silicate

INCI: MAGNESIUM SILICATE

CAS Number
1343-88-0
Function
Absorbent, anticaking, bulking, opacifying, viscosity controlling
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - listed in the VCPA (Voluntary Cosmetic Product Ingredient) database; also used in pharmaceuticals and food (GRAS)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Magnesium Silicate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 800 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 800 mg/kg bw/day oral dog Short Term Toxicity COSMOS_DB

Expert Verdict

Closely related to the talc mineral family - potential asbestos contamination in crude mineral sources is the primary concern; must be sourced and tested to ensure asbestos-free status; inhalation of fine powder should be avoided. Mineral origin; high oil- and moisture-absorption capacity; functions as a thickener in emulsions and a flow agent in powder systems

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Concern Level: Moderate

Regulatory Flags

fda_food_additive

Frequently Asked Questions

Is Magnesium Silicate safe in cosmetics?

Closely related to the talc mineral family - potential asbestos contamination in crude mineral sources is the primary concern; must be sourced and tested to ensure asbestos-free status; inhalation of fine powder should be avoided. Mineral origin; high oil- and moisture-absorption capacity; functions as a thickener in emulsions and a flow agent in powder systems The EU classifies Magnesium Silicate as "prohibited". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database.

Is Magnesium Silicate allowed in the EU?

Magnesium Silicate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Magnesium Silicate do in cosmetics?

Magnesium Silicate functions as: Absorbent, anticaking, bulking, opacifying, viscosity controlling. It is classified as a cosmetic ingredient in our database. CAS number: 1343-88-0.

What is the Margin of Safety for Magnesium Silicate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Magnesium Silicate?

The NOAEL (No Observed Adverse Effect Level) for Magnesium Silicate is 800 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.

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