Good Cosmetic Ingredient Sensitization Data

Achillea Millefolium Extract

INCI: ACHILLEA MILLEFOLIUM EXTRACT

CAS Number
84082-83-7
Function
Skin conditioning, astringent, cleansing, soothing, antioxidant, anti-inflammatory, hair conditioning, tonic
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR assessed safe (amended 2013/2016) at current use concentrations when formulated to be nonsensitizing. Not FDA-regulated as a drug or sunscreen active. Subject to general cosmetic safety substantiation under 21 CFR 740.10. VCRP registrations: 135 product formulations (83 leave-on, 47 rinse-off, 5 bath). No FDA-specific concentration limits.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Achillea Millefolium Extract based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
botanical
EU Allergen Listed
no
Patch Test Positive Rate
0.3%
Cross-reactivity Group
compositae-group
Reaction Type
contact-dermatitis

Source: IVDK; ESSCA; NACDG

Expert Verdict

Achillea Millefolium Extract (CAS 84082-83-7) is safe for use in cosmetics when formulated to be nonsensitizing, per CIR amended conclusion (2013, published 2016). Not listed in EU prohibited/restricted annexes. Verify sesquiterpene lactone and linalool content with supplier CoA before use.

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Concern Level: Low

Regulatory Flags

asteraceae-family sensitization-risk linalool-present alpha-peroxyachifolid no-dermal-absorption-data no-sccs-opinion eu-annex-iii-allergen-constituent botanical-extract cir-reviewed vcrp-registered

Frequently Asked Questions

Is Achillea Millefolium Extract safe in cosmetics?

Achillea Millefolium Extract (CAS 84082-83-7) is safe for use in cosmetics when formulated to be nonsensitizing, per CIR amended conclusion (2013, published 2016). Not listed in EU prohibited/restricted annexes. Verify sesquiterpene lactone and linalool content with supplier CoA before use. The EU classifies Achillea Millefolium Extract as "permitted". Safety rating: GOOD.

Is Achillea Millefolium Extract allowed in the EU?

Achillea Millefolium Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Achillea Millefolium Extract do in cosmetics?

Achillea Millefolium Extract functions as: Skin conditioning, astringent, cleansing, soothing, antioxidant, anti-inflammatory, hair conditioning, tonic. It is classified as a cosmetic ingredient in our database. CAS number: 84082-83-7.

What is the Margin of Safety for Achillea Millefolium Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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