Maytenus Macrocarpa Bark Extract

INCI: MAYTENUS MACROCARPA BARK EXTRACT

CAS Number
Not assigned
Function
Antimicrobial, antioxidant, skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no FDA prohibition or restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Maytenus macrocarpa (known as "chuchuhuasi" in traditional Amazonian medicine) contains bioactive alkaloids and triterpenes. These actives may pose irritation risk at high concentrations. Thorough safety assessment per EU Article 10/11 is recommended given limited CIR review data. Traditionally used in South American ethnomedicine; the bark is rich in phenolic compounds, proanthocyanidins, and maytansinoid-type triterpenoids with documented anti-inflammatory activity. Available as a COSMOS-el...

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Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Maytenus Macrocarpa Bark Extract safe in cosmetics?

Maytenus macrocarpa (known as "chuchuhuasi" in traditional Amazonian medicine) contains bioactive alkaloids and triterpenes. These actives may pose irritation risk at high concentrations. Thorough safety assessment per EU Article 10/11 is recommended given limited CIR review data. Traditionally used in South American ethnomedicine; the bark is rich in phenolic compounds, proanthocyanidins, and maytansinoid-type triterpenoids with documented anti-inflammatory activity. Available as a COSMOS-el... The EU classifies Maytenus Macrocarpa Bark Extract as "permitted". Safety rating: MODERATE.

Is Maytenus Macrocarpa Bark Extract allowed in the EU?

Maytenus Macrocarpa Bark Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Maytenus Macrocarpa Bark Extract do in cosmetics?

Maytenus Macrocarpa Bark Extract functions as: Antimicrobial, antioxidant, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Maytenus Macrocarpa Bark Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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