Is MCE (S87) safe in cosmetics?
MCE (S87) has a safety rating of "GOOD" in our database. EU status: restricted. US status: permitted.
Good
Cosmetic Ingredient
MCE (S87)
Also known as: Acetic acid, 2-cyano-2-[3-[(3-methoxypropyl)amino]-2-cyclohexen-1-ylidene]-, 2-ethoxyethyl ester, (2Z)-, 2-ethoxyethyl 2-cyano-2-[(1Z)-3-[(3-methoxypropyl)amino]cyclohex-2-en-1-ylidene]acetate, EC No.: 700-860-3
INCI: METHOXYPROPYLAMINO CYCLOHEXENYLIDENE ETHOXYETHYLCYANOACETATE
MCE (S87) (CAS 1419401-88-9) is a cosmetic cosmetic ingredient functioning as Insufficient data. NOAEL 250 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: restricted, max 3%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 1419401-88-9 →
Auto-generated CPSR Part A draft with source citations
Function
Insufficient data
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
2-ethoxyethyl (2Z)-2-cyano-2-[3-(3-methoxypropylamino)cyclohex-2-en-1-ylidene]acetate
InChIKey
NPNDSRGIZUPLNP-PEZBUJJGSA-N
Regulatory Status
EU EU Status
restricted
EU Max Conc.
3%
US US Status
permitted
US Notes
No specific restrictions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for MCE (S87).
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for MCE (S87) across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex VI — Permitted UV Filters
Max: 3%
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
KR Korea MFDS Annex 2 (Restricted)
Category: UV Filter. Max: 3%.
SA Saudi SFDA (VI - UV Filters)
Max: 0.03.
BRIN Brazil/India Cosmetics
India: Permitted UV Filter · max 0.03
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| BR | permitted_uv_filter | 3 | Sunscreen products |
Expanded Dermal Absorption Data
Cross-database dermal penetration: EPA Dryad physics-based, Roberts Mendeley permeation, and SCCS-aggregated measured values.
Aggregated DA Values (1 records across 5 sources)
| Type | DA % | Method | Skin Model | SCCS Ref |
|---|---|---|---|---|
| measured_sccs_opinion | 2.65% | - | - | SCCS/1605/19 |
Additional Ingredient Properties
1 property record from structured ingredient metadata.
sunscreen_uv
{"cas_number": "1419401-88-9", "uv_filter_type": "organic_UVA", "chemical_class": "other", "absorption_spectrum_nm_range": "340-400", "peak_absorption_wavelength_nm": "385", "molar_extinction_coefficient": "71000", "critical_wavelength_nm": "395", "UVA_PF": "28-46", "SPF_contribution_per_percent": "2.8", "photostability_rating": "photostable", "photodegradation_half_life_hours": ">24", "photostabi…
Expert Verdict
Expert safety assessment and concern-level summary for MCE (S87).
Regulatory Flags
EU Restricted
SCCS Review
Dermal Absorption
View details ->| Absorption % | Method | Vehicle |
|---|---|---|
| 2.65% | SCCS opinion extraction | - |
Known Synonyms
Acetic acid, 2-cyano-2-[3-[(3-methoxypropyl)amino]-2-cyclohexen-1-ylidene]-, 2-ethoxyethyl ester, (2Z)-
2-ethoxyethyl 2-cyano-2-[(1Z)-3-[(3-methoxypropyl)amino]cyclohex-2-en-1-ylidene]acetate
EC No.: 700-860-3
Frequently Asked Questions
Is MCE (S87) allowed in the EU?
MCE (S87) EU regulatory status: restricted. Maximum allowed concentration: 3%. This is based on EU Regulation 1223/2009 and its amendments.
What does MCE (S87) do in cosmetics?
MCE (S87) functions as: Insufficient data. It is classified as a cosmetic ingredient in our database. CAS number: 1419401-88-9.
Is MCE (S87) used outside cosmetics?
MCE (S87) also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check MCE (S87) compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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