Is MCE (S87) safe in cosmetics?
MCE (S87) has a safety rating of "GOOD" in our database. EU status: restricted. US status: permitted.
Also known as: Acetic acid, 2-cyano-2-[3-[(3-methoxypropyl)amino]-2-cyclohexen-1-ylidene]-, 2-ethoxyethyl ester, (2Z)-, 2-ethoxyethyl 2-cyano-2-[(1Z)-3-[(3-methoxypropyl)amino]cyclohex-2-en-1-ylidene]acetate, EC No.: 700-860-3
INCI: METHOXYPROPYLAMINO CYCLOHEXENYLIDENE ETHOXYETHYLCYANOACETATE
MCE (S87) (CAS 1419401-88-9) is a cosmetic cosmetic ingredient functioning as Insufficient data. EU Regulation 1223/2009 status: restricted, max 3%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 1419401-88-9 →
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Margin of Safety, dermal absorption, and sensitization profile summaries for MCE (S87).
Calculate MoS for your specific formulation with the MoS Calculator.
A margin-of-safety result previously shown for MCE (S87) has been withdrawn pending re-verification. We don't display safety verdicts we can't fully substantiate from the primary SCCS source — so this entry is being re-checked rather than shown unverified.
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| BR | permitted_uv_filter | 3 | Sunscreen products |
Cross-database dermal penetration: EPA Dryad physics-based, Roberts Mendeley permeation, and SCCS-aggregated measured values.
| Type | DA % | Method | Skin Model | SCCS Ref |
|---|---|---|---|---|
| measured_sccs_opinion | 2.65% | - | - | SCCS/1605/19 |
Preliminary editorial summary for MCE (S87) — not a computed safety verdict. See the sourced toxicological data above.
| Absorption % | Method | Vehicle |
|---|---|---|
| 2.65% | SCCS opinion extraction | - |
MCE (S87) has a safety rating of "GOOD" in our database. EU status: restricted. US status: permitted.
MCE (S87) EU regulatory status: restricted. Maximum allowed concentration: 3%. This is based on EU Regulation 1223/2009 and its amendments.
MCE (S87) functions as: Insufficient data. It is classified as a cosmetic ingredient in our database. CAS number: 1419401-88-9.
MCE (S87) also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
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