Melia Azedarach Seed Extract

INCI: MELIA AZEDARACH SEED EXTRACT

CAS Number
Function
Skin conditioning, Antimicrobial
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes No specific FDA restrictions; caution advised — chinaberry plant contains limonoid toxins (meliatoxins) and cytotoxic compounds in fruit; topical seed extract use requires safety substantiation

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Chinaberry seed extract with antimicrobial and conditioning properties; limited cosmetic safety data available and adequate safety substantiation required before use due to presence of toxic limonoids in the plant.

⚠️
Concern Level: Moderate

Regulatory Flags

plant-extract antimicrobial skin-conditioning caution limonoids cytotoxic-plant limited-data

Frequently Asked Questions

Is Melia Azedarach Seed Extract safe in cosmetics?

Chinaberry seed extract with antimicrobial and conditioning properties; limited cosmetic safety data available and adequate safety substantiation required before use due to presence of toxic limonoids in the plant. The EU classifies Melia Azedarach Seed Extract as "permitted". Safety rating: MODERATE.

Is Melia Azedarach Seed Extract allowed in the EU?

Melia Azedarach Seed Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Melia Azedarach Seed Extract do in cosmetics?

Melia Azedarach Seed Extract functions as: Skin conditioning, Antimicrobial. It is classified as a cosmetic ingredient in our database. CAS number: —.

What is the Margin of Safety for Melia Azedarach Seed Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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