Meroxapol 171
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Meroxapol 171. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 25000 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 30000 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 480 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 3000 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 1000 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 200 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 500 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 1000 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 1000 mg/kg bw/day | oral | dog | Subchronic | COSMOS_DB |
| NOAEL | 40 mg/kg bw/day | oral | dog | Subchronic | COSMOS_DB |
Expert Verdict
PPG(12)–PEG(4)–PPG(12) monomer ratio with very low EO content and high hydrophobicity. Lower 1,4-dioxane residual risk due to minimal ethoxylation. May exhibit poorer water solubility; verify emulsion stability in formulations.
Regulatory Flags
Frequently Asked Questions
Is Meroxapol 171 safe in cosmetics?
PPG(12)–PEG(4)–PPG(12) monomer ratio with very low EO content and high hydrophobicity. Lower 1,4-dioxane residual risk due to minimal ethoxylation. May exhibit poorer water solubility; verify emulsion stability in formulations. The EU classifies Meroxapol 171 as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.
Is Meroxapol 171 allowed in the EU?
Meroxapol 171 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Meroxapol 171 do in cosmetics?
Meroxapol 171 functions as: Anti-streaking agent; Binder; Cleaning agent; Defoamer; Dispersing agent; Drier; Emulsifier; Filler; Humectant; Lubricating agent; Solubility enhancer; Solvent; Surface modifier; Surfactant (surface active agent); Thickening agent; Viscosity modifier; Wetting agent (non-aqueous). It is classified as a cosmetic ingredient in our database. CAS number: 9003-11-6.
What is the Margin of Safety for Meroxapol 171?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Meroxapol 171?
The NOAEL (No Observed Adverse Effect Level) for Meroxapol 171 is 25000 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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