Good Cosmetic Ingredient NOAEL Data

Meroxapol 174

INCI: MEROXAPOL 174

CAS Number
9003-11-6
Function
Surfactant – cleansing; Surfactant – emulsifying
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — no specific restriction under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Meroxapol 174. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 25000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 30000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 480 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 3000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 1000 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 200 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 500 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 1000 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 1000 mg/kg bw/day oral dog Subchronic COSMOS_DB
NOAEL 40 mg/kg bw/day oral dog Subchronic COSMOS_DB

Expert Verdict

Monomer ratio: PPG(12)–PEG(23)–PPG(12). Moderate EO content with balanced HLB. Standard 1,4-dioxane controls apply (≤10 ppm).

⚠️
Concern Level: Low

Regulatory Flags

epa_safer_alternative fda_food_additive

Frequently Asked Questions

Is Meroxapol 174 safe in cosmetics?

Monomer ratio: PPG(12)–PEG(23)–PPG(12). Moderate EO content with balanced HLB. Standard 1,4-dioxane controls apply (≤10 ppm). The EU classifies Meroxapol 174 as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.

Is Meroxapol 174 allowed in the EU?

Meroxapol 174 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Meroxapol 174 do in cosmetics?

Meroxapol 174 functions as: Surfactant – cleansing; Surfactant – emulsifying. It is classified as a cosmetic ingredient in our database. CAS number: 9003-11-6.

What is the Margin of Safety for Meroxapol 174?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Meroxapol 174?

The NOAEL (No Observed Adverse Effect Level) for Meroxapol 174 is 25000 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.

Compliance Tools

Check Meroxapol 174 compliance across multiple jurisdictions:

🔬
Ingredient Decoder
Paste a full ingredient list for instant analysis
 🌸
82 Allergen Checker
Check for EU declarable fragrance allergens
 🧪
Substance Compliance
Check compliance across 55 jurisdictions
 🧮
MoS Calculator
Calculate Margin of Safety using SCCS methodology
 ⚗️
Heavy Metal Limits
Compare limits across jurisdictions

Related Ingredients

AMP-C8-18 Perfluoroalkylethyl Phosphate
Poor
Steareth-5
Good
Potassium Cocoyl Taurate
Good
PEG/PPG-4/2 Propylheptyl Ether
Good
PEG/PPG-28/30 Copolymer
Good
Browse all 30,000+ ingredients →
📱

Is Meroxapol 174 in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Meroxapol 174 in your formulation.

Ingredient Decoder MoS Calculator