Meroxapol 255

INCI: MEROXAPOL 255

CAS Number
9003-11-6 (generic CAS for polyoxyethylene-polyoxypropylene block copolymers)
Function
Surfactant (cleansing), emulsifier, solubilizer - a nonionic block copolymer used to stabilize emulsions and solubilize hydrophobic ingredients.
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed in cosmetics; no prohibition or restriction.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Generally regarded as low toxicity; nonionic surfactants of this class are well-tolerated; potential for mild skin degreasing at high concentrations; standard ocular irritation testing recommended for eye-area products.. Meroxapols are "reverse" poloxamers - block copolymers with a central polyoxyethylene (PEO) block flanked by polyoxypropylene (PPO) blocks (PPO-PEO-PPO), as opposed to poloxamers which are PEO-PPO-PEO. The "255" designation specifies the molecular weight and PEO/PPO ratio. Th...

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Concern Level: High

Frequently Asked Questions

Is Meroxapol 255 safe in cosmetics?

Generally regarded as low toxicity; nonionic surfactants of this class are well-tolerated; potential for mild skin degreasing at high concentrations; standard ocular irritation testing recommended for eye-area products.. Meroxapols are "reverse" poloxamers - block copolymers with a central polyoxyethylene (PEO) block flanked by polyoxypropylene (PPO) blocks (PPO-PEO-PPO), as opposed to poloxamers which are PEO-PPO-PEO. The "255" designation specifies the molecular weight and PEO/PPO ratio. Th... The EU classifies Meroxapol 255 as "permitted". Safety rating: MODERATE.

Is Meroxapol 255 allowed in the EU?

Meroxapol 255 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Meroxapol 255 do in cosmetics?

Meroxapol 255 functions as: Surfactant (cleansing), emulsifier, solubilizer - a nonionic block copolymer used to stabilize emulsions and solubilize hydrophobic ingredients.. It is classified as a cosmetic ingredient in our database. CAS number: 9003-11-6 (generic CAS for polyoxyethylene-polyoxypropylene block copolymers).

What is the Margin of Safety for Meroxapol 255?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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