Methionine

INCI: METHIONINE

CAS Number
63-68-3 (L-methionine)
Function
Antioxidant, Hair Conditioning, Skin Conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - No restrictions; essential amino acid with GRAS status in food

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

No significant safety concerns; naturally occurring essential amino acid. Essential sulfur-containing amino acid; synthetic origin in cosmetics; provides antioxidant benefits and supports keratin structure

โš ๏ธ
Concern Level: Moderate

Regulatory Flags

natural-origin

Frequently Asked Questions

Is Methionine safe in cosmetics?

No significant safety concerns; naturally occurring essential amino acid. Essential sulfur-containing amino acid; synthetic origin in cosmetics; provides antioxidant benefits and supports keratin structure The EU classifies Methionine as "permitted". Safety rating: MODERATE.

Is Methionine allowed in the EU?

Methionine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methionine do in cosmetics?

Methionine functions as: Antioxidant, Hair Conditioning, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 63-68-3 (L-methionine).

What is the Margin of Safety for Methionine?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Methionine in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Methionine in your formulation.