Regulatory Status
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Safety Data
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Expert Verdict
Amine-functional PEGs may form nitrosamines in the presence of nitrosating agents - formulators must ensure the product does not contain nitrosating precursors; standard PEG ethoxylation impurity considerations. A very high molecular weight PEG (125 EO units, ~5,500 g/mol) with a terminal amine group; the amine provides cationic character at acidic pH, enabling electrostatic interaction with skin/hair surfaces; often serves as a reactive intermediate for PEG-peptide conjugates
Regulatory Flags
Frequently Asked Questions
Is Methoxy PEG-125 Amine safe in cosmetics?
Amine-functional PEGs may form nitrosamines in the presence of nitrosating agents - formulators must ensure the product does not contain nitrosating precursors; standard PEG ethoxylation impurity considerations. A very high molecular weight PEG (125 EO units, ~5,500 g/mol) with a terminal amine group; the amine provides cationic character at acidic pH, enabling electrostatic interaction with skin/hair surfaces; often serves as a reactive intermediate for PEG-peptide conjugates The EU classifies Methoxy PEG-125 Amine as "prohibited". Safety rating: MODERATE.
Is Methoxy PEG-125 Amine allowed in the EU?
Methoxy PEG-125 Amine EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Methoxy PEG-125 Amine do in cosmetics?
Methoxy PEG-125 Amine functions as: Surfactant, emulsifying (based on its amine-terminated PEG structure). It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned/available.
What is the Margin of Safety for Methoxy PEG-125 Amine?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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