Methoxy PEG-450 Amido Hydroxysuccinimidyl Succinamate

INCI: METHOXY PEG-450 AMIDO HYDROXYSUCCINIMIDYL SUCCINAMATE

CAS Number
Not confirmed from databases accessed
Function
Hair conditioning, surfactant - cleansing
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not prohibited

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Very high molecular weight polymer (~20,000 Da with 450 EO units) - generally considered low risk for skin penetration; reactive NHS ester group should be fully reacted in final product; standard PEG 1,4-dioxane concern. The hydroxysuccinimidyl succinamate moiety is a reactive group designed for protein/keratin binding - enables durable conditioning effects on hair; synthetic origin; solid PEG consistency serves as a consistency enhancer

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Concern Level: Moderate

Regulatory Flags

peg-ingredient

Frequently Asked Questions

Is Methoxy PEG-450 Amido Hydroxysuccinimidyl Succinamate safe in cosmetics?

Very high molecular weight polymer (~20,000 Da with 450 EO units) - generally considered low risk for skin penetration; reactive NHS ester group should be fully reacted in final product; standard PEG 1,4-dioxane concern. The hydroxysuccinimidyl succinamate moiety is a reactive group designed for protein/keratin binding - enables durable conditioning effects on hair; synthetic origin; solid PEG consistency serves as a consistency enhancer The EU classifies Methoxy PEG-450 Amido Hydroxysuccinimidyl Succinamate as "permitted". Safety rating: MODERATE.

Is Methoxy PEG-450 Amido Hydroxysuccinimidyl Succinamate allowed in the EU?

Methoxy PEG-450 Amido Hydroxysuccinimidyl Succinamate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methoxy PEG-450 Amido Hydroxysuccinimidyl Succinamate do in cosmetics?

Methoxy PEG-450 Amido Hydroxysuccinimidyl Succinamate functions as: Hair conditioning, surfactant - cleansing. It is classified as a cosmetic ingredient in our database. CAS number: Not confirmed from databases accessed.

What is the Margin of Safety for Methoxy PEG-450 Amido Hydroxysuccinimidyl Succinamate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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