Is Methoxy PEG-450 Maleimide safe in cosmetics?
Methoxy PEG-450 Maleimide has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Methoxy PEG-450 Maleimide
INCI: METHOXY PEG-450 MALEIMIDE
Methoxy PEG-450 Maleimide (CAS General mPEG-maleimide CAS: 99126-64-4 (covers various MW); specific CAS for the 450 EO unit variant not separately confirmed) is a cosmetic cosmetic ingredient functioning as Hair conditioning, protein conjugation agent (maleimide group is. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
Auto-generated CPSR Part A draft with source citations
CAS Number
General mPEG-maleimide CAS: 99126-64-4 (covers various MW); specific CAS for the 450 EO unit variant not separately confirmed
View industrial chemical safety profile →
Function
Hair conditioning, protein conjugation agent (maleimide group is thiol-reactive, binds to cysteine residues in keratin)
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not prohibited
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Methoxy PEG-450 Maleimide.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Methoxy PEG-450 Maleimide.
Regulatory Flags
potential-allergen
peg-ingredient
Frequently Asked Questions
Is Methoxy PEG-450 Maleimide allowed in the EU?
Methoxy PEG-450 Maleimide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Methoxy PEG-450 Maleimide do in cosmetics?
Methoxy PEG-450 Maleimide functions as: Hair conditioning, protein conjugation agent (maleimide group is thiol-reactive, binds to cysteine residues in keratin). It is classified as a cosmetic ingredient in our database. CAS number: General mPEG-maleimide CAS: 99126-64-4 (covers various MW); specific CAS for the 450 EO unit variant not separately confirmed.
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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