Methoxy-PEG-7 Rutinyl Succinate

INCI: METHOXY-PEG-7 RUTINYL SUCCINATE

CAS Number
380151-83-7
Function
Surfactant (washing-active substance); also described as skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - not prohibited; falls under general cosmetic ingredient safety requirements

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

No significant safety flags identified; PEGylated derivatives carry a theoretical concern for 1,4-dioxane contamination from ethoxylation processes - relevant to your ongoing dioxane work. A PEGylated derivative of rutin (rutoside, a quercetin glycoside naturally occurring in buckwheat, formerly known as vitamin P) esterified with succinic acid. The PEG-7 chain improves water solubility while retaining rutin's antioxidant activity. The methoxy cap reduces reactivity of the terminal hydroxyl

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Concern Level: Moderate

Regulatory Flags

peg-ingredient

Frequently Asked Questions

Is Methoxy-PEG-7 Rutinyl Succinate safe in cosmetics?

No significant safety flags identified; PEGylated derivatives carry a theoretical concern for 1,4-dioxane contamination from ethoxylation processes - relevant to your ongoing dioxane work. A PEGylated derivative of rutin (rutoside, a quercetin glycoside naturally occurring in buckwheat, formerly known as vitamin P) esterified with succinic acid. The PEG-7 chain improves water solubility while retaining rutin's antioxidant activity. The methoxy cap reduces reactivity of the terminal hydroxyl The EU classifies Methoxy-PEG-7 Rutinyl Succinate as "permitted". Safety rating: MODERATE.

Is Methoxy-PEG-7 Rutinyl Succinate allowed in the EU?

Methoxy-PEG-7 Rutinyl Succinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methoxy-PEG-7 Rutinyl Succinate do in cosmetics?

Methoxy-PEG-7 Rutinyl Succinate functions as: Surfactant (washing-active substance); also described as skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 380151-83-7.

What is the Margin of Safety for Methoxy-PEG-7 Rutinyl Succinate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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