NOAEL Studies Cosmetic Ingredient

Methyl Benzoylformate NOAEL Studies

INCI: METHYL BENZOYLFORMATE

CAS: 15206-55-0

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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NTP_ICE_acute_oral 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_acute_oral LD50 =6800 mg/kg bw Rat oral acute Rat Acute Oral Toxicity ECHA ChemProp (undated); record_id=acute_oral_2989; row=16527; data_type=In Vivo; mixture=Chemical; chemical_name=Benzeneacetic acid, .alpha.-oxo-, methyl ester; preferred_name=Benzeneacetic acid, .alpha.-oxo-, methyl ester; dtxsid=DTXSID9065867; url=https://echa.europa.eu/; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9065867; source_file=acute_oral.xlsx
NTP_ICE_acute_oral LD50 <10000 mg/kg bw Rat oral acute Rat Acute Oral Toxicity record_id=acute_oral_2991; row=16526; data_type=In Vivo; mixture=Chemical; chemical_name=Benzeneacetic acid, .alpha.-oxo-, methyl ester; preferred_name=Benzeneacetic acid, .alpha.-oxo-, methyl ester; dtxsid=DTXSID9065867; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9065867; source_file=acute_oral.xlsx
ToxValDB_ECHA_IUCLID 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECHA_IUCLID NOAEL =1000 mg/kg bw/day Rat oral short-term; 14 days short-term QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7ca9ee4b0a7c65d222a55; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/6562/7/6/2?documentUUID=e98a67fd-d84d-4231-944e-429782c73f0a; YEAR=2014; ORIGINAL_YEAR=2014; TOXICOLOGICAL_EFFECT=clinical biochemistry|haematology|organ weights and organ / body weight ratios; TOXICOLOGICAL_EFFECT_CATEGORY=clinical chemistry|hematology|organ weight; STUDY_GROUP=ECHA IUCLID:15834105:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_8a7ed2de2aea025674b0e924ab923e5c
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 23F2045STG UNII - - - chemical {"approval_status":null,"molecular_formula":"C9H8O3","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"23F2045STG"}
openFDA substances FDA UNII substance identifier 23F2045STG UNII - - - chemical {"approval_status":null,"molecular_formula":"C9H8O3","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"23F2045STG"}
openFDA substances FDA UNII substance identifier 23F2045STG UNII - - - chemical {"approval_status":null,"molecular_formula":"C9H8O3","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"23F2045STG"}
openFDA substances FDA UNII substance identifier 23F2045STG UNII - - - chemical {"approval_status":null,"molecular_formula":"C9H8O3","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"23F2045STG"}