Moderate Cosmetic Ingredient NOAEL Data

Methyl Benzoylformate

INCI: METHYL BENZOYLFORMATE

CAS Number
15206-55-0
Function
UV absorber in cosmetics; primarily known as a photoinitiator in industrial UV-curing applications
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status prohibited
🇺🇸 US Status permitted
US Notes Allowed - no prohibition; not a listed OTC sunscreen active

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Methyl Benzoylformate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 1000 mg/kg bw/day oral rat oral REACH
NOAEL 1000 mg/kg bw/day oral rat oral REACH

Expert Verdict

May cause allergic skin reaction (GHS H317) ; skin sensitization potential; primarily an industrial chemical with limited cosmetic use data. Molecular formula C₉H₈O₃; liquid at room temperature (MP ~17°C); initiates polymerization under UV - dual-use as UV absorber in cosmetics and photoinitiator in industrial chemistry

⚠️
Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Methyl Benzoylformate safe in cosmetics?

May cause allergic skin reaction (GHS H317) ; skin sensitization potential; primarily an industrial chemical with limited cosmetic use data. Molecular formula C₉H₈O₃; liquid at room temperature (MP ~17°C); initiates polymerization under UV - dual-use as UV absorber in cosmetics and photoinitiator in industrial chemistry The EU classifies Methyl Benzoylformate as "prohibited". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database.

Is Methyl Benzoylformate allowed in the EU?

Methyl Benzoylformate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Methyl Benzoylformate do in cosmetics?

Methyl Benzoylformate functions as: UV absorber in cosmetics; primarily known as a photoinitiator in industrial UV-curing applications. It is classified as a cosmetic ingredient in our database. CAS number: 15206-55-0.

What is the Margin of Safety for Methyl Benzoylformate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Methyl Benzoylformate?

The NOAEL (No Observed Adverse Effect Level) for Methyl Benzoylformate is 1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.

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