Methyl Hesperidin

INCI: METHYL HESPERIDIN

CAS Number
11013-97-1 (verify via CosIng; this is the commonly listed CAS for methylated hesperidin mixtures).
Function
Skin conditioning, antioxidant. Listed in CosIng with skin-conditioning function.
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no specific prohibition or restriction in cosmetics.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Hesperidin is a well-known citrus bioflavonoid with a strong safety profile. The methylated form improves water solubility. No significant safety concerns reported at typical cosmetic use levels.. Methylated derivative of hesperidin (a flavanone glycoside abundant in citrus peel). Methylation dramatically increases water solubility compared to native hesperidin. Known for capillary-strengthening (venotonic) properties, antioxidant activity, and potential skin-brightening effects. Popular in J...

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Concern Level: Moderate

Frequently Asked Questions

Is Methyl Hesperidin safe in cosmetics?

Hesperidin is a well-known citrus bioflavonoid with a strong safety profile. The methylated form improves water solubility. No significant safety concerns reported at typical cosmetic use levels.. Methylated derivative of hesperidin (a flavanone glycoside abundant in citrus peel). Methylation dramatically increases water solubility compared to native hesperidin. Known for capillary-strengthening (venotonic) properties, antioxidant activity, and potential skin-brightening effects. Popular in J... The EU classifies Methyl Hesperidin as "permitted". Safety rating: MODERATE.

Is Methyl Hesperidin allowed in the EU?

Methyl Hesperidin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methyl Hesperidin do in cosmetics?

Methyl Hesperidin functions as: Skin conditioning, antioxidant. Listed in CosIng with skin-conditioning function.. It is classified as a cosmetic ingredient in our database. CAS number: 11013-97-1 (verify via CosIng; this is the commonly listed CAS for methylated hesperidin mixtures)..

What is the Margin of Safety for Methyl Hesperidin?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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