Methyl Perfluoroisobutyl Ether

INCI: METHYL PERFLUOROISOBUTYL ETHER

CAS Number
163702-07-6 (commonly reported under the same CAS as the mixture; the individual isobutyl isomer may be referenced separately in some databases)
Function
Solvent, Viscosity Controlling Agent (same functional class as the n-butyl isomer)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA specifically names methyl perfluoroisobutyl ether alongside methyl perfluorobutyl ether as common PFAS ingredients found in cosmetics. Allowed but under MoCRA assessment.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Same PFAS persistence and environmental concerns as the n-butyl isomer. Both isomers are typically present together in commercial products.. Branched-chain (isobutyl) isomer of the fluorinated ether; co-occurs commercially with the n-butyl isomer; provides identical functional characteristics

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Concern Level: Moderate

Frequently Asked Questions

Is Methyl Perfluoroisobutyl Ether safe in cosmetics?

Same PFAS persistence and environmental concerns as the n-butyl isomer. Both isomers are typically present together in commercial products.. Branched-chain (isobutyl) isomer of the fluorinated ether; co-occurs commercially with the n-butyl isomer; provides identical functional characteristics The EU classifies Methyl Perfluoroisobutyl Ether as "permitted". Safety rating: MODERATE.

Is Methyl Perfluoroisobutyl Ether allowed in the EU?

Methyl Perfluoroisobutyl Ether EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methyl Perfluoroisobutyl Ether do in cosmetics?

Methyl Perfluoroisobutyl Ether functions as: Solvent, Viscosity Controlling Agent (same functional class as the n-butyl isomer). It is classified as a cosmetic ingredient in our database. CAS number: 163702-07-6 (commonly reported under the same CAS as the mixture; the individual isobutyl isomer may be referenced separately in some databases).

What is the Margin of Safety for Methyl Perfluoroisobutyl Ether?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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