Is Ethylene Distearamide safe in cosmetics?
Ethylene Distearamide has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Ethylene Distearamide
Also known as: Octadecanamide, N,N'-1,2-ethanediylbis-, N,N'-Ethylenebisoctadecanamide, Acrowax C, Advawachs 280, EINECS 203-755-6 (+7 more)
INCI: ETHYLENE DISTEARAMIDE
Ethylene Distearamide (CAS 110-30-5) is a cosmetic cosmetic ingredient functioning as Viscosity controlling, opacifying, slip agent, anti-blocking agent. NOAEL 1000 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 110-30-5 →
Auto-generated CPSR Part A draft with source citations
Function
Viscosity controlling, opacifying, slip agent, anti-blocking agent
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
N-[2-(octadecanoylamino)ethyl]octadecanamide
InChIKey
RKISUIUJZGSLEV-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — not restricted under 21 CFR; FDA-cleared for indirect food contact
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ethylene Distearamide.
Calculate MoS for your specific formulation with the MoS Calculator.
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Short-term Exposure Effects
The substance is mildly irritating to the eyes, skin and respiratory tract.
Routes of Exposure
The substance can be absorbed into the body by inhalation of dust.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Ethylene Distearamide across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
ICSC Safety Card
1112
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Anti-adhesive/cohesive
Anti-static agent
Binder
Crystal growth modifiers (nucleating agents)
Dispersing agent
Lubricating agent
No specific technical function
Plasticizer
Processing aids not otherwise specified
Stabilizing agent
Regulatory List Membership (1)
FDA Indirect Food Contact Additives
Expert Verdict
Expert safety assessment and concern-level summary for Ethylene Distearamide.
Known Synonyms
Octadecanamide, N,N'-1,2-ethanediylbis-
N,N'-Ethylenebisoctadecanamide
Acrowax C
Advawachs 280
EINECS 203-755-6
Ethylenebisstearoamide
Ethylenebis(stearylamide)
Ethylenediamine bisstearamide
Ethylenediamine steardiamide
Ethylenedistearamide
Nopcowax 22-DS
UNII-603RP8TB9A
Chemical Function
Surface modifier
Viscosity modifier
Stabilizing agent
Lubricating agent
Processing aids not otherwise specified
Regulatory Lists
Indirect additives food contact (10/2018)
Europe; plastic_additive
drinking_water; Europe; manufacturing; plastic_additive
drinking_water; Europe; manufacturing; plastic_additive
inert_ingredient; non_food_use; Pesticides
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Ethylene Distearamide allowed in the EU?
Ethylene Distearamide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ethylene Distearamide do in cosmetics?
Ethylene Distearamide functions as: Viscosity controlling, opacifying, slip agent, anti-blocking agent. It is classified as a cosmetic ingredient in our database. CAS number: 110-30-5.
Is Ethylene Distearamide used outside cosmetics?
Ethylene Distearamide also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Ethylene Distearamide compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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