Moderate Cosmetic Ingredient NOAEL Data GHS Classified

Ethylene Distearamide

INCI: ETHYLENE DISTEARAMIDE

CAS Number
110-30-5
Function
Viscosity controlling, opacifying, slip agent, anti-blocking agent
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not restricted under 21 CFR; FDA-cleared for indirect food contact

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Ethylene Distearamide. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 1000 mg/kg bw/day oral rat oral REACH

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The substance is mildly irritating to the eyes, skin and respiratory tract.
Routes of Exposure
The substance can be absorbed into the body by inhalation of dust.

Expert Verdict

Ethylene distearamide is a permitted rheology modifier with adequate margin of safety and low absorption potential.

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Concern Level: Moderate

Frequently Asked Questions

Is Ethylene Distearamide safe in cosmetics?

Ethylene distearamide is a permitted rheology modifier with adequate margin of safety and low absorption potential. The EU classifies Ethylene Distearamide as "permitted". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.

Is Ethylene Distearamide allowed in the EU?

Ethylene Distearamide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ethylene Distearamide do in cosmetics?

Ethylene Distearamide functions as: Viscosity controlling, opacifying, slip agent, anti-blocking agent. It is classified as a cosmetic ingredient in our database. CAS number: 110-30-5.

What is the Margin of Safety for Ethylene Distearamide?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Ethylene Distearamide?

The NOAEL (No Observed Adverse Effect Level) for Ethylene Distearamide is 1000 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.

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