Regulatory Status
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Safety Data
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Expert Verdict
CIR (Cosmetic Ingredient Review) has assessed adenosine-related ingredients as skin-conditioning agents; MTA is a natural metabolite with generally favorable safety profile; used at 0.05-2% in formulations. Chemically 5'-deoxy-5'-(methylthio)adenosine, a natural metabolite of S-adenosylmethionine; patent literature describes antireddening, dermoprotective, and melanin-modulating activity; can function as an antagonist to melanin production receptors
Regulatory Flags
Frequently Asked Questions
Is Methylthioadenosine safe in cosmetics?
CIR (Cosmetic Ingredient Review) has assessed adenosine-related ingredients as skin-conditioning agents; MTA is a natural metabolite with generally favorable safety profile; used at 0.05-2% in formulations. Chemically 5'-deoxy-5'-(methylthio)adenosine, a natural metabolite of S-adenosylmethionine; patent literature describes antireddening, dermoprotective, and melanin-modulating activity; can function as an antagonist to melanin production receptors The EU classifies Methylthioadenosine as "permitted". Safety rating: MODERATE.
Is Methylthioadenosine allowed in the EU?
Methylthioadenosine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Methylthioadenosine do in cosmetics?
Methylthioadenosine functions as: Skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 2457-80-9.
What is the Margin of Safety for Methylthioadenosine?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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