Moderate Cosmetic Ingredient NOAEL Data

Myrrh Extract (Commiphora Myrrha)

INCI: COMMIPHORA MYRRHA RESIN EXTRACT

CAS Number
84929-26-0
Function
Botanical / Natural ingredient
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
EU Max Conc. 0.2%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR safety assessed

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Myrrh Extract (Commiphora Myrrha). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 100 mg/kg bw/day oral rat oral REACH
NOAEL 500 mg/kg bw/day oral rat oral REACH

Expert Verdict

Myrrh Extract is restricted in the EU with a maximum concentration of 0.2%, permitted in the US with CIR safety assessment, but insufficient safety data is available and further assessment is recommended.

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Concern Level: Moderate

Regulatory Flags

EU Restricted eu_children_restricted

Frequently Asked Questions

Is Myrrh Extract (Commiphora Myrrha) safe in cosmetics?

Myrrh Extract is restricted in the EU with a maximum concentration of 0.2%, permitted in the US with CIR safety assessment, but insufficient safety data is available and further assessment is recommended. The EU classifies Myrrh Extract (Commiphora Myrrha) as "restricted". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database.

Is Myrrh Extract (Commiphora Myrrha) allowed in the EU?

Myrrh Extract (Commiphora Myrrha) EU regulatory status: restricted. Maximum allowed concentration: 0.2%. This is based on EU Regulation 1223/2009 and its amendments.

What does Myrrh Extract (Commiphora Myrrha) do in cosmetics?

Myrrh Extract (Commiphora Myrrha) functions as: Botanical / Natural ingredient. It is classified as a Cosmetic Ingredient in our database. CAS number: 84929-26-0.

What is the Margin of Safety for Myrrh Extract (Commiphora Myrrha)?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Myrrh Extract (Commiphora Myrrha)?

The NOAEL (No Observed Adverse Effect Level) for Myrrh Extract (Commiphora Myrrha) is 100 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.

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