Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
3 study endpoints found for o-Cymen-5-ol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 15000 ppm | oral | rat | oral | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 10 other | oral | mouse | oral | REACH |
Expert Verdict
o-Cymen-5-ol is a restricted preservative permitted at concentrations up to 0.5% in the EU with no specific restrictions in the US.
Regulatory Flags
Frequently Asked Questions
Is o-Cymen-5-ol safe in cosmetics?
o-Cymen-5-ol is a restricted preservative permitted at concentrations up to 0.5% in the EU with no specific restrictions in the US. The EU classifies o-Cymen-5-ol as "restricted". Safety rating: MODERATE. 3 toxicological study endpoint(s) are available in our database.
Is o-Cymen-5-ol allowed in the EU?
o-Cymen-5-ol EU regulatory status: restricted. Maximum allowed concentration: 0.5%. This is based on EU Regulation 1223/2009 and its amendments.
What does o-Cymen-5-ol do in cosmetics?
o-Cymen-5-ol functions as: preservative in cosmetic products. It is classified as a Preservative in our database. CAS number: 39660-61-2.
What is the Margin of Safety for o-Cymen-5-ol?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for o-Cymen-5-ol?
The NOAEL (No Observed Adverse Effect Level) for o-Cymen-5-ol is 15000 ppm based on a oral study via oral route in rat. A total of 3 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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