Good Cosmetic Ingredient NOAEL Data

OCTRIZOLE

CAS Number
3147-75-9
Function
Uv Absorber
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status Permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status Not specifically regulated
US Notes Not an approved OTC sunscreen active ingredient; may be used as a UV stabilizer for product protection at low levels

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Toxicological Studies

3 study endpoints found for OCTRIZOLE. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOEL 1000 ppm oral rat oral REACH
NOAEL 30 mg/kg bw/day oral rat oral REACH
NOAEL 5658 mg/kg bw/day oral rat oral REACH

Expert Verdict

OCTRIZOLE is listed in the EU CosIng database with functions: Uv Absorber It is permitted in the EU without specific restrictions.

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Concern Level: Low

Regulatory Flags

cosing-sourced eu-permitted uv-filter needs-enrichment ifra_fragrance

Frequently Asked Questions

Is OCTRIZOLE safe in cosmetics?

OCTRIZOLE is listed in the EU CosIng database with functions: Uv Absorber It is permitted in the EU without specific restrictions. The EU classifies OCTRIZOLE as "Permitted". Safety rating: GOOD. 3 toxicological study endpoint(s) are available in our database.

Is OCTRIZOLE allowed in the EU?

OCTRIZOLE EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does OCTRIZOLE do in cosmetics?

OCTRIZOLE functions as: Uv Absorber. It is classified as a cosmetic ingredient in our database. CAS number: 3147-75-9.

What is the NOAEL for OCTRIZOLE?

The NOAEL (No Observed Adverse Effect Level) for OCTRIZOLE is 1000 ppm based on a oral study via oral route in rat. A total of 3 study endpoints are available. Source: REACH.

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