Moderate Cosmetic Ingredient GHS Classified

p-Chloro-m-cresol

INCI: P-CHLORO-M-CRESOL

CAS Number
59-50-7
Function
Preservative, antimicrobial
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
EU Max Conc. 0.2%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA permitted in cosmetics; no specific monograph restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The substance is irritating to the eyes, skin and respiratory tract.
Long-term Exposure Effects
Repeated or prolonged contact may cause skin sensitization.
Routes of Exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

Expert Verdict

Contact sensitizer requiring declaration and testing; restricted to rinse-off and non-mucosal applications; preservation efficacy testing required at use level

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Concern Level: Moderate

Regulatory Flags

potential-allergen preservative eu_cosing_listed

Frequently Asked Questions

Is p-Chloro-m-cresol safe in cosmetics?

Contact sensitizer requiring declaration and testing; restricted to rinse-off and non-mucosal applications; preservation efficacy testing required at use level The EU classifies p-Chloro-m-cresol as "permitted". Safety rating: MODERATE.

Is p-Chloro-m-cresol allowed in the EU?

p-Chloro-m-cresol EU regulatory status: permitted. Maximum allowed concentration: 0.2%. This is based on EU Regulation 1223/2009 and its amendments.

What does p-Chloro-m-cresol do in cosmetics?

p-Chloro-m-cresol functions as: Preservative, antimicrobial. It is classified as a cosmetic ingredient in our database. CAS number: 59-50-7.

What is the Margin of Safety for p-Chloro-m-cresol?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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