NOAEL Studies
Cosmetic Ingredient
P-METHYLAMINOPHENOL SULFATE NOAEL Studies
CAS: 150-75-4
Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.
SCCS Opinion 6 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| SCCS Opinion | NOAEL | =0.047 | mg/kg | rat | oral | prenatal | developmental toxicity | p.22 |
| SCCS Opinion | NOAEL | =5 | mg/kg/day | - | - | - | NOAEL study | p.21 |
| SCCS Opinion | NOAEL | =5 | mg/kg | rat | oral | prenatal | developmental toxicity | p.22 |
| SCCS Opinion | NOAEL | =10 | mg/kg/day | - | - | Chronic | carcinogenicity | p.14 |
| SCCS Opinion | NOAEL | =10 | mg/kg bw/day | rat | oral | prenatal | developmental toxicity | p.22 |
| SCCS Opinion | NOAEL | =125 | mg/kg/day | - | - | - | NOAEL study | p.21 |
Regulatory source 6 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| Regulatory source | - | 5 | mg/kg/day | - | - | - | - | p.21 |
| Regulatory source | - | 125 | mg/kg/day | - | - | - | - | p.21 |
| Regulatory source | carcinogenicity | 10 | mg/kg/day | - | - | Chronic | carcinogenicity | p.14 |
| Regulatory source | developmental toxicity | =0.047 | mg/kg | rat | oral | prenatal | developmental toxicity | p.22 |
| Regulatory source | developmental toxicity | =5 | mg/kg | rat | oral | prenatal | developmental toxicity | p.22 |
| Regulatory source | developmental toxicity | 10 | mg/kg bw/day | rat | oral | prenatal | developmental toxicity | p.22 |
openFDA substances 2 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| openFDA substances | FDA UNII substance identifier | D3W0VWG12M | UNII | - | - | - | chemical | - |
| openFDA substances | FDA UNII substance identifier | 11W1883EFB | UNII | - | - | - | chemical | - |