Moderate Cosmetic Ingredient GHS Classified Sensitization Data

P-METHYLAMINOPHENOL SULFATE

CAS Number
150-75-4
Function
Hair Dyeing
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status Restricted
EU Max Conc. III/223
🇺🇸 US Status permitted
US Notes CIR: S - IJT 27(Suppl. 2):93-128, 2008

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The substance is irritating to the eyes and skin.
Long-term Exposure Effects
Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the blood. This may result in lesions of blood cells.
Routes of Exposure
The substance can be absorbed into the body by ingestion.

Sensitization Profile

Contact sensitization data for P-METHYLAMINOPHENOL SULFATE based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
dye
EU Allergen Listed
no
Patch Test Positive Rate
0.3%
Cross-reactivity Group
para-amino-group
Reaction Type
contact-dermatitis

Source: IVDK; NACDG; ESSCA

Expert Verdict

P-METHYLAMINOPHENOL SULFATE is listed in the EU CosIng database with functions: Hair Dyeing It is restricted under EU Cosmetics Regulation. Restriction: III/223.

⚠️
Concern Level: Medium

Regulatory Flags

cosing-sourced eu-restricted needs-enrichment

Frequently Asked Questions

Is P-METHYLAMINOPHENOL SULFATE safe in cosmetics?

P-METHYLAMINOPHENOL SULFATE is listed in the EU CosIng database with functions: Hair Dyeing It is restricted under EU Cosmetics Regulation. Restriction: III/223. The EU classifies P-METHYLAMINOPHENOL SULFATE as "Restricted". Safety rating: MODERATE.

Is P-METHYLAMINOPHENOL SULFATE allowed in the EU?

P-METHYLAMINOPHENOL SULFATE EU regulatory status: Restricted. Maximum allowed concentration: III/223. This is based on EU Regulation 1223/2009 and its amendments.

What does P-METHYLAMINOPHENOL SULFATE do in cosmetics?

P-METHYLAMINOPHENOL SULFATE functions as: Hair Dyeing. It is classified as a cosmetic ingredient in our database. CAS number: 150-75-4.

Compliance Tools

Check P-METHYLAMINOPHENOL SULFATE compliance across multiple jurisdictions:

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Substance Compliance
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Heavy Metal Limits
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