Palmitoyl Tripeptide-3 (= Palmitoyl Tripeptide-5)

INCI: PALMITOYL TRIPEPTIDE-3

CAS Number
623172-56-5 (Palmitoyl Tripeptide-5); also referenced as 147732-56-7
Function
Skin conditioning, smoothing, humectant; stimulates collagen via TGF-β
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes CIR reviewed — safe as used in cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Palmitoyl Tripeptide-3 is an older or alternate name for Palmitoyl Tripeptide-5; verify the correct name on your raw material CoA to ensure proper CPNP and FDA labeling.

⚠️
Concern Level: Low

Frequently Asked Questions

Is Palmitoyl Tripeptide-3 (= Palmitoyl Tripeptide-5) safe in cosmetics?

Palmitoyl Tripeptide-3 is an older or alternate name for Palmitoyl Tripeptide-5; verify the correct name on your raw material CoA to ensure proper CPNP and FDA labeling. The EU classifies Palmitoyl Tripeptide-3 (= Palmitoyl Tripeptide-5) as "permitted". Safety rating: GOOD.

Is Palmitoyl Tripeptide-3 (= Palmitoyl Tripeptide-5) allowed in the EU?

Palmitoyl Tripeptide-3 (= Palmitoyl Tripeptide-5) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Palmitoyl Tripeptide-3 (= Palmitoyl Tripeptide-5) do in cosmetics?

Palmitoyl Tripeptide-3 (= Palmitoyl Tripeptide-5) functions as: Skin conditioning, smoothing, humectant; stimulates collagen via TGF-β. It is classified as a cosmetic ingredient in our database. CAS number: 623172-56-5 (Palmitoyl Tripeptide-5); also referenced as 147732-56-7.

What is the Margin of Safety for Palmitoyl Tripeptide-3 (= Palmitoyl Tripeptide-5)?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

📱

Is Palmitoyl Tripeptide-3 (= Palmitoyl Tripeptide-5) in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Palmitoyl Tripeptide-3 (= Palmitoyl Tripeptide-5) in your formulation.