Palmitoyl Tripeptide-38

INCI: PALMITOYL TRIPEPTIDE-38

CAS Number
1101175-36-3 (active); also cited as 1447824-23-8 in some sources
Function
Anti-wrinkle, anti-aging matrikine-mimetic; regulates cell activity, wound repair, and tissue remodeling
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically restricted; CIR group review applies

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Dual CAS numbers in circulation (1101175-36-3 and 1447824-23-8); confirm with supplier which applies to your specific trade material. Known commercially as Matrixyl Synthe'6.

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Concern Level: Low

Frequently Asked Questions

Is Palmitoyl Tripeptide-38 safe in cosmetics?

Dual CAS numbers in circulation (1101175-36-3 and 1447824-23-8); confirm with supplier which applies to your specific trade material. Known commercially as Matrixyl Synthe'6. The EU classifies Palmitoyl Tripeptide-38 as "permitted". Safety rating: GOOD.

Is Palmitoyl Tripeptide-38 allowed in the EU?

Palmitoyl Tripeptide-38 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Palmitoyl Tripeptide-38 do in cosmetics?

Palmitoyl Tripeptide-38 functions as: Anti-wrinkle, anti-aging matrikine-mimetic; regulates cell activity, wound repair, and tissue remodeling. It is classified as a cosmetic ingredient in our database. CAS number: 1101175-36-3 (active); also cited as 1447824-23-8 in some sources.

What is the Margin of Safety for Palmitoyl Tripeptide-38?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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