Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
8 study endpoints found for PEG-2 Stearamine. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOEL | 500 ppm | oral | rat | oral | REACH |
| NOAEL | 13 mg/kg bw/day | oral | dog | oral | REACH |
| NOAEL | >100 mg/kg bw/day | oral | rat | oral | REACH |
| NOEL | 500 ppm | oral | rat | oral | REACH |
| NOAEL | 13 mg/kg bw/day | oral | dog | oral | REACH |
| NOAEL | >100 mg/kg bw/day | oral | rat | oral | REACH |
| NOEL | 5 mg/kg bw/day | oral | rat | oral | REACH |
| NOEL | 5 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Low MW PEG with plausible dermal penetration; 1,4-dioxane and ethylene oxide residuals present; amine functionality may form nitrosamines under specific conditions; avoid contact with nitrosating agents and use on compromised skin is not recommended.
Regulatory Flags
Frequently Asked Questions
Is PEG-2 Stearamine safe in cosmetics?
Low MW PEG with plausible dermal penetration; 1,4-dioxane and ethylene oxide residuals present; amine functionality may form nitrosamines under specific conditions; avoid contact with nitrosating agents and use on compromised skin is not recommended. The EU classifies PEG-2 Stearamine as "permitted". Safety rating: MODERATE. 8 toxicological study endpoint(s) are available in our database.
Is PEG-2 Stearamine allowed in the EU?
PEG-2 Stearamine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does PEG-2 Stearamine do in cosmetics?
PEG-2 Stearamine functions as: Emulsifying, antistatic. It is classified as a cosmetic ingredient in our database. CAS number: 10213-78-2.
What is the Margin of Safety for PEG-2 Stearamine?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for PEG-2 Stearamine?
The NOAEL (No Observed Adverse Effect Level) for PEG-2 Stearamine is 500 ppm based on a oral study via oral route in rat. A total of 8 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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