GOOD Cosmetic Ingredient

PEG-25 Stearate

Also known as: Poly(oxy-1,2-ethanediyl), .alpha.-(1-oxooctadecyl)-.omega.-hydroxy-, Cremophor A, Crill 20,21,22,23, Emcol H 35-A, Empilan CP-100 (+15 more)

INCI: PEG-25 STEARATE

PEG-25 Stearate (CAS 9004-99-3) is a cosmetic cosmetic ingredient functioning as Emulsifying, Surfactant, Humectant. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in food safety data.

View industrial chemical safety profile for CAS 9004-99-3 →

CAS Number
9004-99-3
View industrial chemical safety profile →
Function
Emulsifying, Surfactant, Humectant
Editorial assessment
GOOD
Preliminary editorial note — not a computed safety verdict.

Chemistry & Identifiers

ChEBI: CHEBI:32027 UNII: 0V73PIX5YC Wikidata: Q41874783

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes CIR assessed PEG stearates as safe up to 10%; slight dermal irritation at 100%; oral LD50 >10 g/kg; avoid on damaged skin

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for PEG-25 Stearate.

Calculate MoS for your specific formulation with the MoS Calculator.

EPA ToxValDB — Toxicity Values

5 toxicity values from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).

Endpoint Value Species Route Duration Source
LD50 >10680 mg/kg Rabbit oral - ChemIDplus
LD50 >13350 mg/kg Rabbit oral - ChemIDplus
LD50 =47170 mg/kg Rat oral - ChemIDplus
LD50 =57850 mg/kg Rat oral - ChemIDplus
LD50 >20000 mg/kg Rat oral - ChemIDplus

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Anti-static agent Cleaning agent Defoamer Dispersing agent Emulsifier Fragrance Humectant Lubricating agent Solvent Surfactant (surface active agent)
Regulatory List Membership (6)
EU Regulated in Personal Care EU Restricted for Children (Cosmetics) IFRA Fragrance Transparency List EPA Safer Chemical Ingredients List (SCIL) FDA Substances Added to Food (EAFUS) FDA Indirect Food Contact Additives

Editorial summary

Preliminary editorial summary for PEG-25 Stearate — not a computed safety verdict. See the sourced toxicological data above.

Regulatory Flags

peg-compound ethoxylated avoid-damaged-skin eu_children_restricted epa_safer_alternative ifra_fragrance fda_food_additive

Known Synonyms

Poly(oxy-1,2-ethanediyl), .alpha.-(1-oxooctadecyl)-.omega.-hydroxy- Cremophor A Crill 20,21,22,23 Emcol H 35-A Empilan CP-100 Empilan CQ-100 Emulphor VT-650 Emunon 3115 Glycol polyethylene monostearate #200 Glycol, polyethylene monostearate #6000 Ionet MS-1000 Kessco X-211 Lipal 400-S Lipo-Peg 4-S Nikkol MYS-25 Nissan Nonion S-2 NSC 31811 alpha-(1-Oxooctadecyl)-omega-hydroxypoly(oxy-1,2-ethanediyl) PEG-150 stearate PEG-40 stearate

Chemical Function

Solvent Surfactant (surface active agent) Cleaning agent

Regulatory Lists

children; Europe; Personal care children; Europe; Personal care - general moisturizing - hand/body lotion Europe; Personal care Europe; Personal care Europe; Personal care Canada; pharmaceutical CEDI Indirect additives food contact (10/2018) children; Europe; Personal care children; Europe; Personal care - general moisturizing - hand/body lotion IFRA Transparency active_ingredient; Pesticides SCIL (9/2019) food_additive; Substances Added to Food (formerly EAFUS) (2/2019) inert_ingredient; Pesticides inert_ingredient; non_food_use; Pesticides

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in food safety data.

SOURCE EFSA / FDA GRAS food_additives

Food Safety Data

Same-CAS food additive or FDA GRAS records from the core public database.

Food Name
Polyoxyethylene (40) stearate
E Number
E431
ADI
0-25 mg/kg bw mg/kg bw
Food Category
emulsifier
View full food safety profile →

Frequently Asked Questions

Is PEG-25 Stearate safe in cosmetics?

PEG-25 Stearate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.

Is PEG-25 Stearate allowed in the EU?

PEG-25 Stearate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does PEG-25 Stearate do in cosmetics?

PEG-25 Stearate functions as: Emulsifying, Surfactant, Humectant. It is classified as a cosmetic ingredient in our database. CAS number: 9004-99-3.

Is PEG-25 Stearate used outside cosmetics?

PEG-25 Stearate also appears in food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Compliance Tools

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