Moderate Cosmetic Ingredient

PEG/PPG-5/3 Trisiloxane

INCI: PEG/PPG-5/3 TRISILOXANE

CAS Number
Not individually assigned (silicone-polyether hybrid)
Function
Surfactant (superspreading/wetting agent), emulsifying agent
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes No individual CIR monograph. Silicone-PEG/PPG hybrids are not covered by the Alkyl PEG/PPG Ethers review. Supported indirectly by CIR dimethicone/PEG copolymer reviews

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Superspreading properties may enhance penetration of co-formulated actives. Monitor for residual D4/D5 cyclomethicone traces (EU Annex II restricted) and 1,4-dioxane/EO/PO residuals from ethoxylation. Environmental persistence concerns noted for silicone moiety.

⚠️
Concern Level: Moderate

Regulatory Flags

peg-ingredient

Frequently Asked Questions

Is PEG/PPG-5/3 Trisiloxane safe in cosmetics?

Superspreading properties may enhance penetration of co-formulated actives. Monitor for residual D4/D5 cyclomethicone traces (EU Annex II restricted) and 1,4-dioxane/EO/PO residuals from ethoxylation. Environmental persistence concerns noted for silicone moiety. The EU classifies PEG/PPG-5/3 Trisiloxane as "permitted". Safety rating: MODERATE.

Is PEG/PPG-5/3 Trisiloxane allowed in the EU?

PEG/PPG-5/3 Trisiloxane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does PEG/PPG-5/3 Trisiloxane do in cosmetics?

PEG/PPG-5/3 Trisiloxane functions as: Surfactant (superspreading/wetting agent), emulsifying agent. It is classified as a cosmetic ingredient in our database. CAS number: Not individually assigned (silicone-polyether hybrid).

What is the Margin of Safety for PEG/PPG-5/3 Trisiloxane?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check PEG/PPG-5/3 Trisiloxane compliance across multiple jurisdictions:

🔬
Ingredient Decoder
Paste a full ingredient list for instant analysis
 🌸
82 Allergen Checker
Check for EU declarable fragrance allergens
 🧪
Substance Compliance
Check compliance across 55 jurisdictions
 🧮
MoS Calculator
Calculate Margin of Safety using SCCS methodology
 ⚗️
Heavy Metal Limits
Compare limits across jurisdictions

Related Ingredients

Sodium Tallamphopropionate
Good
Stearyl Acetyl Glutamate
Good
Sodium Caprylyl Sulfonate
Good
Glycol Ricinoleate
Excellent
Isosteareth-10
Good
Browse all 30,000+ ingredients →
📱

Is PEG/PPG-5/3 Trisiloxane in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for PEG/PPG-5/3 Trisiloxane in your formulation.

Ingredient Decoder MoS Calculator