PEI-45/TMP/Xylene Diisocyanate Crosspolymer

INCI: PEI-45/TMP/XYLENE DIISOCYANATE CROSSPOLYMER

CAS Number
Not assigned (crosspolymer)
Function
Film forming, hair fixative
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically listed by FDA; CIR has reviewed some HDI/isocyanate crosspolymers and found them safe when fully reacted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Dual residual monomer risk (aziridine and xylene diisocyanate); isocyanates are respiratory sensitizers; Certificate of Analysis must confirm both residuals below detection limits

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is PEI-45/TMP/Xylene Diisocyanate Crosspolymer safe in cosmetics?

Dual residual monomer risk (aziridine and xylene diisocyanate); isocyanates are respiratory sensitizers; Certificate of Analysis must confirm both residuals below detection limits The EU classifies PEI-45/TMP/Xylene Diisocyanate Crosspolymer as "restricted". Safety rating: MODERATE.

Is PEI-45/TMP/Xylene Diisocyanate Crosspolymer allowed in the EU?

PEI-45/TMP/Xylene Diisocyanate Crosspolymer EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does PEI-45/TMP/Xylene Diisocyanate Crosspolymer do in cosmetics?

PEI-45/TMP/Xylene Diisocyanate Crosspolymer functions as: Film forming, hair fixative. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (crosspolymer).

What is the Margin of Safety for PEI-45/TMP/Xylene Diisocyanate Crosspolymer?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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