Is Barium Chloride safe in cosmetics?
Barium Chloride has a safety rating of "POOR" in our database. EU status: prohibited. US status: prohibited. 7 toxicological study endpoint(s) are available in our database.
Barium Chloride
Also known as: BaCl2, Barium chloride (BaCl2), EINECS 233-788-1, UNII-0VK51DA1T2
INCI: BARIUM CHLORIDE
Barium Chloride (CAS 10361-37-2) is a cosmetic cosmetic ingredient functioning as Not a cosmetic ingredient. NOAEL 38 mg/kg bw/day (PDF-verified against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 10361-37-2 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Barium Chloride is prohibited in EU cosmetics but has active industrial GHS classifications (H301, H319, H332, H413).
Source: Cosmetics: ingredients.eu status; Chemicals: ghs classifications.signal word/hazard statement code
Function
Not a cosmetic ingredient
Safety Rating
POOR
Regulatory Status
EU EU Status
prohibited
US US Status
prohibited
US Notes
Not permitted for cosmetic use; barium compounds are toxic
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Barium Chloride.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
7 study endpoints found for Barium Chloride. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =38 mg/kg bw/day | oral | Rat | subchronic | ECHA |
| NOAEL | =38.1 mg/kg bw/day | oral | Rat | subchronic | ECHA |
| NOAEL | =45.7 mg/kg bw/day | oral | Rat | subchronic | ECHA |
| NOAEL | =61.1 mg/kg bw/day | oral | Rat | chronic | ECHA |
| NOAEL | =80.9 mg/kg bw/day | oral | Rat | chronic | ECHA |
| NOAEL | =209 mg/kg bw/day | oral | Rat | short-term | ECHA |
| NOAEL | =446 mg/kg bw/day | oral | Rat | chronic | ECHA |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Short-term Exposure Effects
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the nervous system. Exposure could cause hypokalaemia. This may result in cardiac disorders and muscular disorders. Exposure could cause death.
Routes of Exposure
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Barium Chloride across SCCS product categories, with measured dermal absorption where available.
EU CLP Annex VI Harmonized Classification
Legally binding harmonized classification per Regulation (EC) No 1272/2008 (CLP) Annex VI.
Signal Word
Danger
Pictograms
Acute Toxicity
Hazard Class and Category
Acute Tox. 4 *; Acute Tox. 3 *
Hazard Statements
- H332 Harmful if inhaled
- H301 Toxic if swallowed
Inserted via ATP: CLP00
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10,000 - 100,000 tonnes
Substance Type
SUBSTANCE; GROUP
SVHC Candidate
No
Hazard classification: Restricted (Annex XVII)
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| BR | banned | - | - |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
No specific technical function
Expert Verdict
Expert safety assessment and concern-level summary for Barium Chloride.
Regulatory Flags
endocrine_disruptor
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Barium Chloride by CAS number or substance name.
Studies
7
Lowest NOAEL
38 mg/kg bw/day
Highest NOAEL
446 mg/kg bw/day
ECHA
Known Synonyms
BaCl2
Barium chloride (BaCl2)
EINECS 233-788-1
UNII-0VK51DA1T2
Chemical Function
No specific technical function
Regulatory Lists
Canada; consumer_product; Substances in Products - Canada (4/2014)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3184191
Frequently Asked Questions
Is Barium Chloride allowed in the EU?
Barium Chloride EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Barium Chloride do in cosmetics?
Barium Chloride functions as: Not a cosmetic ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 10361-37-2.
What is the NOAEL for Barium Chloride?
The NOAEL (No Observed Adverse Effect Level) for Barium Chloride is =38 mg/kg bw/day based on a subchronic study via oral route in Rat. A total of 7 study endpoints are available. Source: ECHA.
Is Barium Chloride used outside cosmetics?
Barium Chloride also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Barium Chloride have different safety status in cosmetics vs industrial chemicals?
Barium Chloride is prohibited in EU cosmetics but has active industrial GHS classifications (H301, H319, H332, H413).
Compliance Tools
Check Barium Chloride compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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