Regulatory Status
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Safety Data
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Expert Verdict
Structurally analogous to diacetyl; causes bronchiolitis obliterans via inhalation; NIOSH occupational exposure alerts issued; acutely hazardous to respiratory epithelium. Avoid in spray, aerosol, or inhalable product formats; robust inhalation risk assessment essential for CPSR sign-off even in leave-on products.
Regulatory Flags
Frequently Asked Questions
Is Pentanedione safe in cosmetics?
Structurally analogous to diacetyl; causes bronchiolitis obliterans via inhalation; NIOSH occupational exposure alerts issued; acutely hazardous to respiratory epithelium. Avoid in spray, aerosol, or inhalable product formats; robust inhalation risk assessment essential for CPSR sign-off even in leave-on products. The EU classifies Pentanedione as "permitted". Safety rating: POOR.
Is Pentanedione allowed in the EU?
Pentanedione EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Pentanedione do in cosmetics?
Pentanedione functions as: Fragrance / Masking. It is classified as a cosmetic ingredient in our database. CAS number: 600-14-6.
What is the Margin of Safety for Pentanedione?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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