Regulatory Status
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Safety Data
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Expert Verdict
BSE/TSE compliance mandatory — animal-origin enzyme (typically porcine gastric mucosa). Must provide TSE Certificate of Suitability per EU Regulation 1223/2009, Article 15. Proteolytic activity may cause irritation at high concentrations or low pH.
Regulatory Flags
Frequently Asked Questions
Is Pepsin safe in cosmetics?
BSE/TSE compliance mandatory — animal-origin enzyme (typically porcine gastric mucosa). Must provide TSE Certificate of Suitability per EU Regulation 1223/2009, Article 15. Proteolytic activity may cause irritation at high concentrations or low pH. The EU classifies Pepsin as "restricted". Safety rating: GOOD.
Is Pepsin allowed in the EU?
Pepsin EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Pepsin do in cosmetics?
Pepsin functions as: Hair conditioning, skin conditioning (proteolytic enzyme). It is classified as a cosmetic ingredient in our database. CAS number: 9001-75-6.
What is the Margin of Safety for Pepsin?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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