Ephedra Sinica Root Extract

INCI: EPHEDRA SINICA ROOT EXTRACT

CAS Number
84625-37-6 (species-level; root-specific CAS may vary)
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Same scrutiny as Ephedra sinica extract

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Ephedra sinica root extract has a distinct alkaloid profile from aerial parts with potential hypotensive rather than hypertensive activity, but cross-contamination during harvesting is a documented risk requiring full alkaloid panel analysis for EU approval.

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Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Ephedra Sinica Root Extract safe in cosmetics?

Ephedra sinica root extract has a distinct alkaloid profile from aerial parts with potential hypotensive rather than hypertensive activity, but cross-contamination during harvesting is a documented risk requiring full alkaloid panel analysis for EU approval. The EU classifies Ephedra Sinica Root Extract as "prohibited". Safety rating: MODERATE.

Is Ephedra Sinica Root Extract allowed in the EU?

Ephedra Sinica Root Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Ephedra Sinica Root Extract do in cosmetics?

Ephedra Sinica Root Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 84625-37-6 (species-level; root-specific CAS may vary).

What is the Margin of Safety for Ephedra Sinica Root Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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