Regulatory Status
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Safety Data
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Expert Verdict
Primarily a research spin-trap reagent with pharmacological activity (inhibits NF-κB, COX-2, iNOS, and lipid peroxidation) that raises questions about cosmetic suitability; any safety assessment would require custom toxicological testing.
Frequently Asked Questions
Is Phenyl t-Butylnitrone safe in cosmetics?
Primarily a research spin-trap reagent with pharmacological activity (inhibits NF-κB, COX-2, iNOS, and lipid peroxidation) that raises questions about cosmetic suitability; any safety assessment would require custom toxicological testing. The EU classifies Phenyl t-Butylnitrone as "permitted". Safety rating: MODERATE.
Is Phenyl t-Butylnitrone allowed in the EU?
Phenyl t-Butylnitrone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Phenyl t-Butylnitrone do in cosmetics?
Phenyl t-Butylnitrone functions as: Antioxidant (spin trap / free radical scavenger). It is classified as a cosmetic ingredient in our database. CAS number: 3376-24-7 [^1_11].
What is the Margin of Safety for Phenyl t-Butylnitrone?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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