Piper Betle Leaf Extract

INCI: PIPER BETLE LEAF EXTRACT

CAS Number
84775-81-5
Function
Antimicrobial, Deodorant, Masking
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Contains safrole and eugenol; no formal FDA restriction but safety scrutiny advised; not widely used in US cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Extract of betel leaf (Piper betle) with antimicrobial and deodorizing properties; contains safrole (up to ~49% of essential oil) which is restricted in EU cosmetics under Annex III; eugenol is a regulated fragrance allergen; use in leaf extract form at typical concentrations may remain within limits but full safety dossier essential; not recommended for leave-on products without controlled safrole quantification.

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Concern Level: Moderate

Regulatory Flags

safrole_concern fragrance_allergen sensitizer

Frequently Asked Questions

Is Piper Betle Leaf Extract safe in cosmetics?

Extract of betel leaf (Piper betle) with antimicrobial and deodorizing properties; contains safrole (up to ~49% of essential oil) which is restricted in EU cosmetics under Annex III; eugenol is a regulated fragrance allergen; use in leaf extract form at typical concentrations may remain within limits but full safety dossier essential; not recommended for leave-on products without controlled safrole quantification. The EU classifies Piper Betle Leaf Extract as "restricted". Safety rating: MODERATE.

Is Piper Betle Leaf Extract allowed in the EU?

Piper Betle Leaf Extract EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Piper Betle Leaf Extract do in cosmetics?

Piper Betle Leaf Extract functions as: Antimicrobial, Deodorant, Masking. It is classified as a cosmetic ingredient in our database. CAS number: 84775-81-5.

What is the Margin of Safety for Piper Betle Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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