Poloxamer 251

INCI: POLOXAMER 251

CAS Number
9003-11-6 (generic poloxamer CAS)
Function
Surfactant, emulsifying agent
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not included in the CIR 2008 safety assessment

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Poloxamer 251 is a permitted surfactant and emulsifying agent with moderate safety profile and low absorption and sensitization potential.

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Concern Level: Moderate

Frequently Asked Questions

Is Poloxamer 251 safe in cosmetics?

Poloxamer 251 is a permitted surfactant and emulsifying agent with moderate safety profile and low absorption and sensitization potential. The EU classifies Poloxamer 251 as "permitted". Safety rating: MODERATE.

Is Poloxamer 251 allowed in the EU?

Poloxamer 251 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Poloxamer 251 do in cosmetics?

Poloxamer 251 functions as: Surfactant, emulsifying agent. It is classified as a cosmetic ingredient in our database. CAS number: 9003-11-6 (generic poloxamer CAS).

What is the Margin of Safety for Poloxamer 251?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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