Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
3 study endpoints found for Polydipentene. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 5000 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 5000 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| dose_tested | 5000 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
Expert Verdict
Residual limonene content is the critical concern. Limonene auto-oxidizes rapidly and must be tested for limonene hydroperoxide levels. If residual limonene exceeds 0.001% in leave-on products, EU allergen declaration is required. Store under nitrogen to prevent oxidation.
Regulatory Flags
Frequently Asked Questions
Is Polydipentene safe in cosmetics?
Residual limonene content is the critical concern. Limonene auto-oxidizes rapidly and must be tested for limonene hydroperoxide levels. If residual limonene exceeds 0.001% in leave-on products, EU allergen declaration is required. Store under nitrogen to prevent oxidation. The EU classifies Polydipentene as "restricted". Safety rating: MODERATE. 3 toxicological study endpoint(s) are available in our database.
Is Polydipentene allowed in the EU?
Polydipentene EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Polydipentene do in cosmetics?
Polydipentene functions as: Solvent; viscosity controlling agent; plasticizer. It is classified as a cosmetic ingredient in our database. CAS number: 9003-73-0.
What is the Margin of Safety for Polydipentene?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Polydipentene?
The NOAEL (No Observed Adverse Effect Level) for Polydipentene is 5000 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 3 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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